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INDONESIA
INDONESIAN JOURNAL OF PHARMACY
Published by Universitas Gadjah Mada
ISSN : 23389427     EISSN : 23389486     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas Gadjah Mada (UGM) Yogyakarta Indonesia in collaboration with IAI (Ikatan Apoteker Indonesia or Indonesian Pharmacist Association) and only receives manuscripts in English. Indonesian Journal of Pharmacy is Accredited by Directorate General of Higher Education (DGHE) DIKTI No. 58/DIKTI/Kep/2013.
Arjuna Subject : -
Articles 2 Documents
 1 
Search results for , issue " Vol 20 No 1, 2009" : 2 Documents clear
Drug Related Problem (DRP) of Dengue Hemorragic Fever (DHF) medication in pediatric patient` Yasin, Nanang Munif; Sunowo, Joko; Supriyanti, Eri
INDONESIAN JOURNAL OF PHARMACY Vol 20 No 1, 2009
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.374 KB) | DOI: 10.14499/indonesianjpharm0iss0pp27-34

Abstract

Every year, Dengue Hemorrhagic Fever (DHF) is the big problem Indonesian’s government with high incidency and high mortality. It would increased length of stay and high cost. The objectives of this study are to identify drug-related problems in DHF patient include need for additional drug therapy, unnecessary drug therapy, wrong drug, drug interaction, dosage to high, and dosage too low.A prospective study of pediatrics admitted to Pediatric Ward, X Private Hospital Yogyakarta for DHF infections was carried out since February-April 2006. Appropriate descriptive analysis was used.The results showed that unnecessary drug therapy the most drugrelated problems in 22 patient from 65 pediatic patient.The other DRP were dosage too low in 14 patient, dosage too high in 10 patient, wrong drug in 4 patient, and need for additional drug therapy in 2 patient, rescpectively. Antibiotics were the most cause of drug-related problems in DHF patient.Key words : Dengue Hemorrhagic Fever (DHF), Drug-Related Problem (DRP), Antibiotic , Hospital.
Synthesis of a potential angiogenesis inhibitor compound: 2-benzylidene cyclohexane-1,3-dione Istyastono, Enade
INDONESIAN JOURNAL OF PHARMACY Vol 20 No 1, 2009
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjpharm0iss0pp1-8

Abstract

Synthesis of an aromatic cyclic enadione, 2-benzylidene-cyclohexane-1,3-dione (a potential angiogenesis inhibitor), has been done using benzaldehide (50 mmole) and cyclohexane-1,3-dione (50 mmole) as starting materials and NaOH 1.0 N as a catalyst. Odorless and white needle-shape powder has been achieved. The powder was 252.7 mg (2.53 %) and the purity of the powder was 88.81 %. Its melting point was 214.8 oC. The purity of the product was examined by gas chromatography, while the structure elucidation was done using IR spectrometer, 1H-NMR spectrometer, and GC-MS.IR spectrometer showed that the compound had a -C=O bond conjugated to an alkene or a phenyl moiety, methylen groups, and alkene’s -C–H bonds. 1H-NMR spectrometer showed that the compound had benzene moiety and methylen moieties, which were in α and β position to a carbonyl group. GC-MS showed that the molecular weight of the compound was 200 atomic mass unit.Key words: Angiogenesis inhibitor, synthesis, 2-benzylidene-cyclohexane-1,3-dione.

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